DR. PHIL HARTMAN

Publications

 

Publications
(does not include over 80 abstracts from unrefereed journals and meetings):

  • Hartman, Paul A. and Philip S. Hartman. 1976. Coliform analysis at 30C. J. Milk Food Technol. 39,763-767.
  • Hartman, Paul A., Philip S. Hartman and Kevin T. Frey. 1975. Longevity of dehydrated violet red bile agar. Applied Microbiol. 29,295-296.
  • Hartman, Paul A., Philip S. Hartman and Wayne W. Lanz. 1975. Violet red bile 2 agar for stressed coliforms. Applied Microbiol. 29, 537-539.
  • Hartman, P.S. and A. Eisenstark. 1978. Synergistic killing of Escherichia coli by near-UV radiation and hydrogen peroxide: distinction between RecA-repairable and RecA-nonrepairable damage. J. Bacteriol. 133,769-774.
  • Ananthaswamy, H.N., P.S. Hartman and A. Eisenstark. 1979. Synergistic lethality of phage T7 by near-UV radiation and hydrogen peroxide: an action spectrum. Photobiol. Photochem. 29,53-56.
  • Hartman, P.S., A. Eisenstark and P.G. Pauw. 1979. Near-ultraviolet radiation plus hydrogen peroxide inactivation of phage T7: induction of DNA-protein crosslinkage which prevents injection. Proc. Natl. Acad. Sci. U.S.A. 76,3228-3232.
  • Hartman, P.S. and A. Eisenstark. 1980. Killing of Escherichia coli K-12 by near-ultraviolet radiation plus hydrogen peroxide: role of double-strand DNA breaks in the absence of recombinational repair. Mutat. Research 72,31-42.
  • Wang, R.J., H.N. Ananthaswamy, B.T. Nixon, P.S. Hartman and A. Eisenstark. 1980. Induction of single-stranded DNA breaks in human cells by hydrogen peroxide formed in blacklight irradiated medium. Radiat. Res. 82,269-276.
  • Hartman, Philip S. 1981. A model to explain certain near-UV radiation effects. Photochem. Photobiol. 34,39-43.
  • Hartman, Philip S. and A. Eisenstark. 1982. Alternation of bacteriophage attachment capacity by near-UV irradiation. J. Virol. 43,529-532.
  • Hartman, Philip S. and Robert K. Herman. 1982. Radiation-sensitive mutants of Caenorhabditis elegans. Genetics 102,159-178.
  • Hartman, Philip S. and Robert K. Herman. 1982. Somatic damage to the X chromosome of the nematode Caenorhabditis elegans induced by gamma radiation. Molec. gen. Genet. 187.116-119.
  • Herman, Robert K., Claire K. Kari and Philip S. Hartman. 1982. Dominant X-chromosome nondisjunction mutants of Caenorhabditis elegans Genetics 102,379-400.
  • Hartman, Philip S. 1984. UV irradiation of wild type and radiation-sensitive mutants of the nematode Caenorhabditis elegans fertilities, survival, and parental effects. Photochem. Photobiol. 39, 169-175.
  • Hartman, Philip S. 1984. Effects of age and liquid holding on the UV radiation sensitivities of wild-type and mutant Caenorhabditis elegans dauer larvae. Mutat. Res. 132,95-99.
  • Hartman, Philip S. 1985. Epistatic interactions of radiation-sensitive (rad) mutants of C.elegans. Genetics 109,81-93.
  • Hartman, Philip S. 1986. In situ hydrogen peroxide production may account for some near-UV radiation killing of Escherichia coli. Photochem. Photobiol. 43,87-90.
  • Eisenstark, A., R. Buzard and P.S. Hartman. 1986. Effects of hydrogen peroxide and near-UV radiation on bacteriophage. Photochem. Photobiol. 43,603-606.
  • Keller, Cindy, John Calkins, Philip S. Hartman and Claud S. Rupert. 1987. UV Photobiology of the nematode Caenorhabditis elegans: Action spectra, absence of photoreactivation and effects of caffeine. Photochem. Photobiol. 46,483-288.
  • Hartman, Philip S. 1987. Caffeine-resistant mutants of Caenorhabditis elegans. Genetical Research 49,105-110.
  • Hevelone, Julie and Philip S. Hartman. 1987. Isolation and characterization of a nuclease from Caenorhabditis elegans. Biochemical Genetics 26,447-461.
  • Johnson, Thomas and Philip S. Hartman. 1988. Radiation effects on life-span in Caenorhabditis elegans. J. Gerontol. 43B,137-141.
  • Hartman, Philip S., Victoria J. Simpson, Thomas Johnson and David Mitchell. 1988. Radiation sensitivity and DNA repair in Caenorhabditis elegans strains with different mean life spans. Mutat. Res. 208,77-82.
  • Hartman, Philip S., David L. Mitchell, Julie Hevelone and V. Dwarakanath. 1989. Excision repair of UV radiation-induced DNA damage in wild-type Caenorhabditis elegans. Genetics 122, 379-385.
  • Mitchell, David and Philip S. Hartman. 1990. Developmental regulation of DNA repair. BioEssays 12, 74-79.
  • Hartman, Philip S., Betty-Ann Svendsen, Jennifer Reddy and David Mitchell. 1990. DNA repair in the nematode Caenorhabditis elegans. UCLA Symposia on Molecular and Cellular Biology, New Series 123, 67-80 (C.E. Finch and T.E. Johnson, eds.).
  • Hartman, Philip S., Jennifer Reddy and Betty-Ann Svendsen. 1991. Does translesion synthesis explain the UV radiation-resistance of C. elegans embryos. Mutat. Res. 255, 163-173.
  • Hartman, Philip S. 1991. Transillumination can profoundly reduce the transforming ability of plasmid DNA. BioTechniques 11, 747-748.
  • Hartman, Philip S. and Anne Marshall. 1992. Inacivation of wild-type and rad mutant Caenorhabditis elegans by 8-methoypsoralen and near ultraviolet radiation. Photochem. Photobiol. 139, 103-111.
  • Ishii, Naoaki, Norio Suzuki, Philip S. Hartman, and Kenshi Suzuki. 1993. The radiation sensitive mutant rad-8 of Caenorhabditis elegans is hypersensitive to the effects of oxygen on aging and development. Mechanisms of Aging and Development 60, 1-10.
  • Ishii, Naoaki, Norio Suzuki, Philip S. Hartman and Kenshi Suzuki. 1994. The effects of temperature on the longevity of a radiation-sensitive mutant rad-8 of the Nematode Caenorhabditis elegans. J. Gerontol. 49, B117- B120.
  • Ishii, Naoaki, Norio Suzuki, Philip S. Hartman, and Kenshi Suzuki. 1995. The effects of temperature and oxygen on aging of the rad-8 mutant of Caenorhabditis elegans. Journal of Gerontology 49, B117-B120.
  • Hartman, Phil S., Daniel DeWilde, and Vangipuran Dwarakanath, 1995. Genetic and molecular analyses of UV radiation-induced mutations in the fem-3 gene of Caenorhabditis elegans . Photochem. Photobiol. 61, 607-614.
  • Hartman, Phil, Evelyn Childress, and Todd Beyer. 1995. Nematode development is inhibited by methyl viologen and high oxygen concentrations at rates inversely proportional to life span. J. Gerontol. 50A, B322-B326.
  • Jones, Clark and Philip S. Hartman. 1996. Replicon sizes in unirradiated and UV irradiated Caenorhabditis elegans embryos. Photochem. Photobiol. 63: 187-192.
  • Hartman, Phil and Greg Nelson. 1996. Processing of DNA damage in the nematode Caenorhabditis elegans (invited review article). in: DNA damage and repair ---Biochemistry, genetics and cell biology (M. Hoekstra and J.A. Nickoloff, eds.). vol 1, pp. 557-576, Humana Press, New Jersey.
  • Hartman, Phil, Paul Goldstein, Marcella Algarra, Darren Hubbard, and Jared Mabery. 1996. The nematode Caenorhabditis elegans is up to 39 times more sensitive to gamma radiation generated from 137Cs than from 60Co. Mutat. Res. 363, 201-208.
  • Ishii, Naoaki and Phil Hartman. 1998. Aging and resistance to oxidative damage in Caenorhabditis elegans. (http://www.mcmaster.ca/inabigbin/lwc5ab.cgi).
  • Ishii, Naoaki, Michihiko Fujii, Philip S. Hartman, Michio Tsuda, Kayo Yasuda, Nanami Senoo-Matsuda, Sumino Yanase, Dai Ayusawa and Kenshi Suzuki. 1998. A mutation in succinate dehydrongenase cytochrome b causes oxidative stress and aging in nematodes. Nature 394, 694-697.
  • Mills, DeEtta and Philip S. Hartman. 1998. Lethal consequence of simulated solar radiation on the Nematode Caenorhabditis elegans Photochem. Photobiol. 68, 816-823.
  • Nelson, G.A., W.W. Schubert, R.G. Kern, G.A. Karariahs, D. Schranck, P. S. Hartman, A. Hlavacek, E.V. Benton and E.R. Benton. 1999. Modification of Radiogenic damage by microgravity. In: BioRack on Shuttle to Mir. European Sapce Agency Special Publication ESA-SP-1222. E.S.A. Noordwijk, Netherlands, pp. 183-194.
  • Yamase, Sumino, Philip S. Hartman, Atsushi Ito and Naoaki Ishii. 1999. Oxidative stress pretreatment increases the X-radiation resistance of the Nematode Caenorhabditis elegans Mutation Res. 426, 31-39.
  • Ishii, Naoaki and Philip S. Hartman. 2000. Oxidative stress and aging in Caenorhabditis elegans Results and Problems in Cell Differentiation. Vol. 29. the Molecular Genetics of Aging. Pp. 150-163.
  • Phil S. Hartman, Anthony Hlavacek, Honor Wilde, Dan Lewicki, Wayne Schubert, Roger G. Kern, Gayane, A. Kazarinas, Eugene V. Benton, Eric R. Benton and Gregory A. Nelson. 2001. A comparison of mutations induced by accelerated iron particles versus those induced by low earth orbit space radiation in the fem-3 gene of Caenorhabditis elegans. Mutation Res. 474, 47-55.
  • Phil S. Hartman, Naoaki Ishii, Ernst-Bernhard Kayser, Phil G. Morgan and Margaret M. Sedensky. 2001. Mitochondrial mutations differentially affect aging, mutability and anesthetic sensitivity in Caenorhabditis elegans. Mechanisms of Ageing and Development 122,1187-1201.
  • Senoo-Matsuda, Nanami, Kayo Yasuda, Michio Tsudua, Tomoichi Ohkubo, Shinichi Yoshimura, Hiroe Nakazawa, Phil S. Hartman and Naoaki Ishii. 2001. A defect in the cytochrome b large subunit in Complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans. J. Biol. Chem. 276, 41553-41558
  • Naoaki Ishii, Kiyoshi Kita and Phil S. Hartman. 2001. Mitochondrial contributions to aging in the nematode Caenorhabditis elegans. Current Genomics 2, 349-355.
  • Naoaki Ishii, Sataro Goto and Philip S. Hartman. 2002. Protein oxidation during aging of the nematode Caenorhabditis elegans. Free Radical Biology & Medicine 33, 1021-1025.
  • Ichimiya, Harumi, R. Giselle Huet, Phil Hartman, Hisako Amino, Kiyoshi Kita, and Naoaki Ishii. 2002. Complex II inactivation is lethal in the nematode Caenorhabditis elegans. Mitochondrion 2, 191-198.
  • Philip S. Hartman, Naoaki Ishii and Thomas E. Johnson. 2003. Genetic of Aging in the Nematode Caenorhabditis elegans. In: "Chromosomal Instability and Aging. Basic Science and Clinical Implications" (edited by F.M. Hisama, S.M. Weissman and G.M. Martin), Marcell Dekker, Inc. New York, pp. 493-507.
  • Nanami Senoo-Matsuda , Philip S. Hartman , Akira Akatsuka, Shinichi Yoshimura , and Naoaki Ishii. 2003. A Complex II Defect Affects Mitochondrial Structure, Leading to ced-3- and ced-4-dependent Apoptosis and Aging. Journal of Biological Chemistry 278, 22031-22036.
  • Ishii, N., N. Senoo-Matsuda, K. Miyake, K. Yasuda, Phil Hartman and S. Furukawa. 2004. Coenzyme Q can prolong C. elegans lifespan by lowering oxidative stress. Mech. Ageing Develop. 125, 41-46.
  • Ishii, N. and Phil Hartman. 2004. Electron transport and life span in C. elegans. Energy metabolism and Life Span Determination. Advances in Cell Aging and Gerontology. (Mark Mattson, ed). Pp. 177-195. (Elsevier Press).
  • Hartman, Phil, Rebecca Ponder, Herng-Hsiang Lo and Naoaki Ishii. 2004. Mitochondrial oxidative stress can lead to nuclear hypermutability. Mech. Ageing Develop. 125, 417-420.
  • Masaki Kondo, Sumino Yanase, Takamasa Ishii, Philip S. Hartman, Kunihiro Matsumoto, Naoaki Ishii. 2005. The p38 signal transduction pathways participates in the oxidative stress-mediated translocation of DAF-16 to Caenorhabditis elegans nuclei. Mechanisms of Ageing and Development 126:642-647.
  • Masaki Kondo, Nanami Senoo-Matsuda, Sumino Yanase, Takamasa Ishii, Philip S. Hartman, Naoaki Ishii. 2005. Effects of oxidative stress on translocation of DAF-16 in oxygen-sensitive mutants, mev-1 and gas-1 of Caenorhabditis elegans. Mechanisms of Ageing and Development 126: 637- 641.

  • Yasuda, K., T. Ishii, H. Suda, A. Akatsuka, Phil Hartman, S. Goto, M. Miyazawa, N. Ishii. 2006. Age-related changes in Mitochondrial structure and function in Caenorhabditis elegans.  Mechanisms of Ageing and Development 127:763-770 .

  • Ishii, Naoaki, Takamasa Ishii and Philip S. Hartman. 2006. The role of the electron transport gene SDHC on lifespan and cancer. Experimental Gerontology 41:952-956.

  • Hartman, Phil S., Naoaki Ishii. 2007. Chromosome dosage as a life span determinant in Caenorhabditis elegans. Mechanisms of Ageing and Development 128: 437-441.
  • Yamaguchi, T., A. Onodera, K. Yasuda, Y. Nishio, M. Arai, M. Tsuda, M. Miyazawa, Phil Hartman and N. Ishii.  2008.  A low cost and rapid assay system using the free-living nematode Caenorhabditis elegans to determine the effects of Kampo medicines on life span. AATEX 13, 1-10.